Meriç Şimşek - Osmaniye Korkut Ata Üniversitesi
Transkript
Meriç Şimşek Yardımcı Doçent Dr. Gıda Mühendisliği Osmaniye Korkut Ata Üniversitesi, Osmaniye, Türkiye 80000 E-mail: [email protected] Tel.: +90328-827-1000/3661 Ofis: EH Z23 GENEL ARAŞTIRMA ALANLARI Karbonhidratlar ve sağlık Nişasta sindirimi Nişasta sindirim enzimleri SPESİFİK ARAŞTIRMA ALANLARI Doğal botanik bileşiklerle, nişasta sindirim oranının manipülasyonu α-glukosidazlar için doğal botanik inhibitörler Doğal botanik bileşiklerle, α-glukosidazların gen ekspresyonunun modülasyonu Doğal botanik bileşiklerle, protein sentezi, olgunlaşma and hücrelerarası taşıma modülasyonu AKADEMİK GÖREVLER Yardımcı Doçent Dr., Gıda Mühendisliği Osmaniye Korkut Ata Üniversitesi, Osmaniye, Türkiye Ekim 2015-devam Dr. Araştırma Görevlisi, Gıda Mühendisliği Osmaniye Korkut Ata Üniversitesi, Osmaniye, Türkiye Şubat 2015-Ekim 2015 Ziyaretçi Araştırmacı, Laboratory of Molecular and Cellular Immunology and Biology, Kimya Fakültesi San Luis Potosi Üniversitesi, SLP, Meksika Haziran 2015- Eylül 2015 EĞİTİM Doktora, Gıda Bilimi Aralık 2014 Purdue Üniversitesi, West Lafayette, IN, Amerika Tez Başlığı: Inhibition of activities of individual subunits of intestinal Maltase-Glucoamylase and Sucrase-Isomaltase by dietary phenolic compounds for modulating glucose release and gene response Tez Danışmanı: Prof. Dr. Bruce Hamaker Yüksek Lisans, Gıda Mühendisliği Mayıs 2010 Orta Doğu Teknik Üniversitesi, Ankara, Türkiye Tez Başlığı: Microwave Assisted Extraction of Phenolic Compounds from Tomato and Sour Cherry Pomaces Tez Danışmanı: Prof. Dr. S. Gülüm Şumnu M.Simsek: Curriculum Vitae Page 1 Lisans, Gıda Mühendisliği Gaziantep Üniversitesi, Gaziantep, Türkiye Haziran 2007 Erasmus öğrencisi, Gıda Mühendisliği Catholic Üniversitesi, Porto, Portekiz Ağustos 2006 Yoğunlaştırılmış İngilizce Dil Eğitimi Eckerd College, St. Petersburg, FL, Amerika Mayıs 2009-Kasım 2009 YAYINLAR Uluslararası Hakemli Dergilerde Yayınlanan Makaleler Simsek, M., Quezada-Calvillo, R., Ferruzzi, M. G., Nichols, B. L., Hamaker, B. R. (2015). Dietary phenolic compounds selectively inhibit the individual subunits of Maltase-Glucoamylase and Sucrase-Isomaltase with the potential of modulating glucose release. Journal of Agricultural and Food Chemistry, 63, 3873-3879. Simsek, M., Sumnu, G., Sahin, S. (2012). Microwave assisted extraction of phenolic compounds from sour cherry pomace. Separation Science and Technology, 47, 1248-1254. ULUSLARARASI KONFERANS SUNUMLARI Sözel sunumlar Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2012) Natural polyphenols are potential inhibitors of intestinal maltase-glucoamylase for control of glucose release from starch digestion. Annual Meeting of American Association of Cereal Chemists International (AACCI), Holywood, FL, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2013) Gallic acid modifies the expression of intestinal maltase-glucoamylase mRNA but not the enzyme activity. Annual Meeting of Experimental Biology, Boston, MA, USA. Poster sunumlar Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2012). Natural polyphenols are potential inhibitors of intestinal maltase-glucoamylase for control of glucose release from starch digestion. Annual Meeting of American Association of Cereal Chemists International, Holywood, FL, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2013). Different polyphenols have different affinities for C-terminal subunits of maltase-glucoamylase and sucrase-isomaltase for the modulation of glucose release. Annual Meeting of Experimental Biology, Boston, MA, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2013). Differential effects of polyphenols on the expression of intestinal maltase-glucoamylase. Annual Meeting of Institute of Food Technologists, Chicago (IFT), IL, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2013). Different polyphenols have different affinities for maltase of total human intestinal homogenate for the modulation of M.Simsek: Curriculum Vitae Page 2 glucose release. Annual Meeting of American Association of Cereal Chemists International, Albequerque, NM, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2014). Inhibition of individual subunits of maltase-glucoamylase and sucrase-isomaltase by polyphenols. Annual Meeting of Experimental Biology, San Diego, CA, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2014). Maltase activity of individual subunits of recombinant maltase-glucoamylase and sucrase-isomaltase is inhibited differentially by polyphenols. Annual Meeting of Institute of Food Technologists, New Orleans, LA, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2014). Polyphenols have multiple effects on the intestinal α-glucosidases. Annual Meeting of American Association of Cereal Chemists International, Providence, RI, USA. Simsek, M., Quezada-Calvillo, R., Nichols, B. L., Hamaker, B. R. (2015). Distinct inhibitory potencies of dietary phenolic compounds for the mucosal α-glucosidases in the human small intestine. Annual Meeting of Experimental Biology, Boston, MA, USA. Quezada-Calvillo, R., Simsek, M., Juarez, J., Nichols, B. L. (2015). Protein synthesis controls the activity of maltase-glucoamylase and sucrase-isomaltase in non-intestinal tissues. Annual Meeting of Experimental Biology, Boston, MA, USA. BAŞARI VE ÖDÜLLER (2010-2014) Milli Eğitim Bakanlığı Yurtdışı Yükseköğrenim (Doktora) Bursu (2013) AACCI Carbohydrate Division/Megazyme En İyi Poster Ödülü (3.sıra) (2013) AACCI Öğrenci Seyahat Ödülü (2014) Finalist, IFT Carbohydrate Division Graduate Research Paper Competition (2014) AACCI Öğrenci Seyahat Ödülü MESLEKİ DENEYİM FS-453 Gıda Kimyası Lab Purdue Üniversitesi, IN, Amerika ÜYELİKLER Institute of Food Technologists (IFT), Chicago, IL, USA American Society for Nutrition (ASN), Bethesda, MD, USA American Association of Cereal Chemists International (AACCI), Eagan, MN, USA Whistler Center for Carbohydrate Research, West Lafayette, IN, USA Starch Digestion Consortium (SDC), (Multi-national: Waterloo University, Canada; Purdue University, USA; Baylor College, USA and San Luis Potosi University, Mexico; School of Veterinary Medicine, Germany.) M.Simsek: Curriculum Vitae Page 3
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